Tapentadol is a strong pain relief medication that has gained popularity because of its effectiveness. While its therapeutic benefits are well known, it is important to understand the potential side effects of this medication. In this blog, we will discuss the side effects associated with Tapentadol, helping you make an informed decision.

Understanding these adverse effects can guide conversations with your medical provider about any concerns you may have.

What Is Tapentadol?

Tapentadol is a prescription-only opioid medicine used medically to manage moderate to severe pain. It is available in two formulations: immediate-release and extended-release [1]. The immediate-release formulation was approved in 2008, and the extended-release formulation was approved in 2011.

These available formulations of Tapentadol medication are well-known because of their potency and therapeutic benefits.

Common Side Effects Of Tapentadol

The most frequently reported side effects of Tapentadol hydrochloride are as follows [2]:

Nausea and vomiting : Many people report gastrointestinal issues after taking Tapentadol, such as nausea and vomiting. Therefore, take this medication with a meal to avoid these symptoms.

Constipation : Like other opioid pain medicines, Tapentadol can cause constipation in some users. To mitigate these symptoms, increase the intake of fiber-rich foods.

Drowsiness : Taking Tapentadol tablets can cause sleepiness, which may impair your ability to perform tasks that require focus, such as driving.

Headaches : Some people report headaches as a side effect of Tapentadol, which may diminish once the medication gets adjusted to the body.

Dizziness : Feelings of lightheadedness or dizziness after taking Tapentadol pain reliever are common. Therefore, avoid standing up too quickly from a lying or seated position.

Serious Side Effects Of Tapentadol

Although rare, Tapentadol hydrochloride can cause serious side effects in some individuals. Seek immediate medical help if you experience the following side effects after taking the pain medication [3].

Urination problems : Some Tapentadol users may experience changes in their urination pattern, including urinary retention, decreased urination, or difficulty urinating.

Liver issues : Tapentadol can cause liver-related side effects, especially with long-term use of the medicine. Some people may experience elevated liver enzymes, usually reversible once the medication is stopped. In rare cases, more serious liver damage can occur.

Mental health problems : Tapetadol hydrochloride can cause rare mood changes in some individuals, such as anxiety, depression, and confusion.

Low blood pressure or hypotension : Some patients may experience low blood pressure after taking Tapentadol. The symptoms include lightheadedness, fainting, or even fainting in some cases.

Allergic reaction : Some Tapentadol users may experience an allergic reaction after taking it. Symptoms include: swelling, itching, rashes, or trouble breathing.

Long-Term Side Effects Of Tapentadol

Tapentadol use can cause the following side effects if used for a long duration.

Overdosing : One of the most serious concerns associated with the long-term use of Tapentadol is its risk of overdose. Overdosing on the medication can occur due to higher doses than prescribed or combined with other substances that depress the CNS.

The signs and symptoms of overdosing on Tapentadol include – lightheadedness, coughing, loss of consciousness, swelling in the legs and ankles, and decreased awareness.

Risk of withdrawal symptoms : If you abruptly stop taking the opioid pain medicine, you may experience various Tapentadol withdrawal symptoms such as anxiety, tremors, vomiting, runny nose, stomach pain, and cravings. It’s important for you to talk with your health care provider before discontinuing the use of Tapentadol.

Tolerance and dependence : One significant concern with prolonged Tapentadol use is its potential for tolerance, where people require a high amount of the drug to get the same effects.

What Should I Know about Tapentadol Before Using It?

• Do not take Tapentadol unless a medical provider has prescribed it. Take this opioid pain medication as prescribed.
• Do not share Tapentadol with others, even if they have the same condition.
• Keep Tapentadol out of reach of pets and children to prevent them from accidentally taking the medicine.
• Do not cut, break, split, or dissolve Tapentadol tablets. This can increase the risk of an overdose.
• Drink enough water when taking Tapentadol tablets to ensure you entirely swallow the tablet.
• Inform your doctor if the dose of Tapentadol you are taking does not control your pain.
• Tapentadol may harm your unborn baby; therefore, it is crucial to inform your doctor if you are or plan to become pregnant [4].

Conclusion

While Tapentadol is a powerful option for managing moderate to severe pain, it’s essential to be aware of its potential adverse effects. Common side effects like nausea, headaches, or drowsiness may resolve with time, but serious side effects such as allergic reactions should never be ignored. Always use this opioid pain medication under the supervision of your doctor.